Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin-Reference-Cited by-同舟云学术

Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin

Published:2022-09-26 Issue:10 Volume:17 Page:2728-2733
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Zhang Hengxi¹²³⁴⁵,Modenutti Carlos¹⁶⁷,Nekkanti Yelha Phani Kumar⁸⁹,Denis Maxime³⁴,Bermejo Iris A.³⁴^ORCID,Lefèbre Jonathan³⁴⁵,Che Kateryna¹⁰¹¹,Kim Dongyoon¹³⁴,Kagelmacher Marten¹²,Kurzbach Dennis¹⁰^ORCID,Nazaré Marc⁸⁹^ORCID,Rademacher Christoph¹²³⁴^ORCID

Affiliation:

1. Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1 14424 Potsdam, Germany

2. Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany

3. Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria

4. Department of Microbiology and Immunobiology, Max F. Perutz Laboratories, University of Vienna, Dr.-Bohr-Gasse 9, 1030 Vienna, Austria

5. Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (PhaNuSpo), University of Vienna, Universitätsring 1, 1010 Vienna, Austria

6. Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, C1428EHA Buenos Aires, Argentina

7. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET, C1428EHA Buenos Aires, Argentina

8. Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Strasse 10, 13125 Berlin, Germany

9. Berlin Institute of Health (BIH), Anna-Louisa-Karsch-Strasse 2, 10178 Berlin, Germany

10. Faculty of Chemistry, Institute of Biological Chemistry, University of Vienna, Währinger Straße 38, 1090 Vienna, Austria

11. Doctoral School in Chemistry (DoSChem), University of Vienna, Währingerstr. 42, 1090 Vienna, Austria

Funder

Deutscher Akademischer Austauschdienst

Austrian Science Fund

Technische Universit??t Wien

European Commission

Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00626

Reference21 articles.

1. Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin

2. Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cells

3. Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent

4. Molecular Recognition in C‐Type Lectins: The Cases of DC‐SIGN, Langerin, MGL, and L‐Sectin

5. Langerhans cells cross-present antigen derived from skin

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