Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents

Author:

Piano Valentina1,Benjamin Daniel I.2,Valente Sergio3,Nenci Simone1,Marrocco Biagina3,Mai Antonello34,Aliverti Alessandro5,Nomura Daniel K.2,Mattevi Andrea1

Affiliation:

1. Department of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100 Pavia, Italy

2. Program in Metabolic Biology, Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, California 94720, United States

3. Department of Drug Chemistry and Technologies, University “La Sapienza”, P. le A. Moro 5, Roma 00185, Italy

4. Pasteur Institute, Cenci Bolognetti Foundation, P.le A. Moro 5, Roma 00185, Italy

5. Department of Biosciences, University of Milano, Via Festa del Perdono, 7, 20122 Milano, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

American Cancer Society

Ministero dell'Istruzione, dell'Università e della Ricerca

Congressionally Directed Medical Research Programs

Fondazione Telethon

National Cancer Institute

Seventh Framework Programme

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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