Selectively Disrupting m6A-Dependent Protein–RNA Interactions with Fragments-Reference-Cited by-同舟云学术

Selectively Disrupting m6A-Dependent Protein–RNA Interactions with Fragments

Published:2020-02-26 Issue:3 Volume:15 Page:618-625
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Bedi Rajiv Kumar¹,Huang Danzhi¹,Wiedmer Lars¹,Li Yaozong¹^ORCID,Dolbois Aymeric¹,Wojdyla Justyna Aleksandra²,Sharpe May Elizabeth²,Caflisch Amedeo¹^ORCID,Sledz Pawel¹^ORCID

Affiliation:

1. Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland

2. Swiss Light Source, Paul Scherrer Institute, 5232 Villigen, Switzerland

Funder

Vetenskapsr?det

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Universit?t Z?rich

Innosuisse - Schweizerische Agentur f?r Innovationsf?rderung

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00894

Reference20 articles.

1. H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

2. The Emerging Role of RNA as a Therapeutic Target for Small Molecules

3. Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

4. RNA-modifying proteins as anticancer drug targets

5. The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

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