High-Speed Diagnosis of Bacterial Pathogens at the Single Cell Level by Raman Microspectroscopy with Machine Learning Filters and Denoising Autoencoders

Author:

Xu Jiabao1ORCID,Yi Xiaofei23,Jin Guilan23,Peng Di23,Fan Gaoya23,Xu Xiaogang45,Chen Xin45,Yin Huabing6ORCID,Cooper Jonathan M.6,Huang Wei E.1ORCID

Affiliation:

1. Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, U.K.

2. Shanghai Hesen Biotechnology Co., Ltd, Shanghai 201802, China

3. Shanghai D-band Medical Instrument Co., Ltd, Shanghai 201802, China

4. Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, China

5. National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China

6. James Watt School of Engineering, University of Glasgow, Glasgow G12 8LT, U.K.

Funder

Ministry of Science and Technology of the People's Republic of China

Innovate UK

Science and Technology Commission of Shanghai Municipality

Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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