The HPK1 Inhibitor A-745 Verifies the Potential of Modulating T Cell Kinase Signaling for Immunotherapy
Author:
Affiliation:
1. AbbVie Inc., 1 North Waukegan Rd., North Chicago, Illinois 60064, United States
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00819
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1. Functional interactions of HPK1 with adaptor proteins
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3. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase
4. Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase
5. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
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