Biosynthesis of the Sphingolipid Inhibitors Sphingofungins in Filamentous Fungi Requires Aminomalonate as a Metabolic Precursor-Reference-Cited by-同舟云学术

Biosynthesis of the Sphingolipid Inhibitors Sphingofungins in Filamentous Fungi Requires Aminomalonate as a Metabolic Precursor

Published:2022-01-13 Issue:2 Volume:17 Page:386-394
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Bissell Alexander U.¹²,Rautschek Julia¹,Hoefgen Sandra¹,Raguž Luka³⁴,Mattern Derek J.⁵,Saeed Nauman⁶²,Janevska Slavica¹^ORCID,Jojić Katarina¹²,Huang Ying¹²,Kufs Johann E.¹⁷,Herboeck Barbara¹⁴,Guo Huijuan³,Hillmann Falk⁶,Beemelmanns Christine³,Valiante Vito¹^ORCID

Affiliation:

1. Biobricks of Microbial Natural Product Syntheses, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany

2. Faculty of Biological Sciences, Friedrich Schiller University Jena, 07743 Jena, Germany

3. Chemical Biology of Microbe−Host Interactions, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany

4. Faculty of Chemistry and Earth Sciences, Friedrich Schiller University Jena, 07743 Jena, Germany

5. Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany

6. Evolution of Microbial Interactions, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany

7. Bio Pilot Plant, Hans Knöll Institute (HKI), Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Beutenbergstrasse 11a, 07745 Jena, Germany

Funder

Bundesministerium f?r Bildung und Forschung

Deutsche Forschungsgemeinschaft

H2020 European Research Council

European Social Fund ESF ?Europe for Thuringia?

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00839

Reference45 articles.