Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture-Reference-Cited by-同舟云学术

Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture

Published:2022-02-04 Issue:2 Volume:17 Page:299-313
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Svec Riley L.¹,McKee Sydney A.¹,Berry Matthew R.²,Kelly Aya M.¹,Fan Timothy M.²³,Hergenrother Paul J.¹³^ORCID

Affiliation:

1. Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

2. Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

3. Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

Funder

National Cancer Institute

National Institute of General Medical Sciences

University of Illinois

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00022

Reference90 articles.

1. A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme

2. Treatment of Glioblastoma

3. Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)

4. Involvement of the Mismatch Repair System in Temozolomide-Induced Apoptosis

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