PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components-Reference-Cited by-同舟云学术

PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components

Published:2023-03-06 Issue:3 Volume:18 Page:494-507
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Bashore Frances M.¹^ORCID,Foley Caroline A.¹^ORCID,Ong Han Wee¹^ORCID,Rectenwald Justin M.¹,Hanley Ronan P.¹,Norris-Drouin Jacqueline L.¹,Cholensky Stephanie H.¹,Mills Christine A.²,Pearce Kenneth H.¹,Herring Laura E.²^ORCID,Kireev Dmitri¹^ORCID,Frye Stephen V.¹^ORCID,James Lindsey I.¹³^ORCID

Affiliation:

1. Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

2. UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Funder

Lineberger Comprehensive Cancer Center, University of North Carolina

University of North Carolina at Chapel Hill

National Institute on Drug Abuse

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00804

Reference40 articles.