Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering-Reference-Cited by-同舟云学术

Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering

Published:2023-03-09 Issue:4 Volume:18 Page:772-784
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Thakur Avinash K.¹,Miller Stephen E.¹^ORCID,Liau Nicholas P.D.²,Hwang Sunhee¹,Hansen Simon¹^ORCID,de Sousa e Melo Felipe³,Sudhamsu Jawahar²,Hannoush Rami N.¹^ORCID

Affiliation:

1. Department of Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, United States

2. Department of Structural Biology, Genentech, South San Francisco, California 94080, United States

3. Department of Molecular Oncology, Genentech, South San Francisco, California 94080, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00753

Reference63 articles.

1. An LDL-receptor-related protein mediates Wnt signalling in mice

2. Alternative Wnt Signaling Is Initiated by Distinct Receptors

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4. LDL-receptor-related proteins in Wnt signal transduction

5. A new member of the frizzled family from Drosophila functions as a Wingless receptor

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