HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates

Author:

Gaffney Althea1,Nangarlia Aakansha23ORCID,Ang Charles G.2ORCID,Gossert Steven4,Rashad Ahmed Adel Ahmed2ORCID,Hossain Md Alamgir2,Abrams Cameron F.4ORCID,Smith Amos B.1ORCID,Chaiken Irwin2ORCID

Affiliation:

1. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, United States

3. School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, United States

4. Department of Chemical and Biological Engineering, Drexel University, Philadelphia, Pennsylvania 19104, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Reference29 articles.

1. Foundation KF. U.S. Federal Funding for HIV/AIDS: Trends Over Time 2019. Available from: http://files.kff.org/attachment/Fact-Sheet-US-Federal-Funding-for-HIVAIDS-Trends-Over-Time (accessed) November 15th, 2020.

2. WHO. WHO HIV drug resistance report 2012. Available from: https://www.who.int/hiv/pub/drugresistance/report2012/en/ (accessed) November 15th, 2020.

3. Barriers to access to antiretroviral treatment in developing countries: a review

4. Inhibitors of HIV-1 attachment: The discovery and structure–activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore

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