Cysteine Hydropersulfide Inactivates β-Lactam Antibiotics with Formation of Ring-Opened Carbothioic S-Acids in Bacteria-Reference-Cited by-同舟云学术

Cysteine Hydropersulfide Inactivates β-Lactam Antibiotics with Formation of Ring-Opened Carbothioic S-Acids in Bacteria

Published:2021-03-29 Issue:4 Volume:16 Page:731-739
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Ono Katsuhiko¹,Kitamura Yusuke²^ORCID,Zhang Tianli¹,Tsutsuki Hiroyasu¹,Rahman Azizur¹,Ihara Toshihiro²^ORCID,Akaike Takaaki³^ORCID,Sawa Tomohiro¹^ORCID

Affiliation:

1. Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku Kumamoto 860-8556, Japan

2. Division of Materials Science and Chemistry, Faculty of Advanced Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku Kumamoto 860-8555, Japan

3. Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan

Funder

The Association for Research on Lactic Acid Bacteria

Ministry of Education, Science, Sports, and Technology (MEXT), Japan

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00027

Reference40 articles.

1. Microbial Resistance Movements: An Overview of Global Public Health Threats Posed by Antimicrobial Resistance, and How Best to Counter

2. Antibiotic Adjuvants: Rescuing Antibiotics from Resistance