Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development-Reference-Cited by-同舟云学术

Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development

Published:2018-02-01 Issue:3 Volume:13 Page:812-819
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

von Tesmar Alexander¹,Hoffmann Michael¹,Abou Fayad Antoine¹,Hüttel Stephan²,Schmitt Viktoria¹,Herrmann Jennifer¹,Müller Rolf¹^ORCID

Affiliation:

1. Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany

2. Department of Microbial Drugs, Helmholtz Centre for Infection Research and German Centre for Infection Research (DZIF), partner site Hannover/Braunschweig, Inhoffenstrasse 7, 38124 Braunschweig, Germany

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00990

Reference44 articles.

1. Tilivalline, a new pyrrolo[2, 1-c][1,4] benzodiazepine metabolite from klebsiella

2. Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis

3. Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines

4. Production of a unique cytotoxin by Klebsiella oxytoca

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