Dual Allosteric Inhibition of SHP2 Phosphatase-Reference-Cited by-同舟云学术

Dual Allosteric Inhibition of SHP2 Phosphatase

Published:2018-01-05 Issue:3 Volume:13 Page:647-656
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Fodor Michelle¹,Price Edmund¹,Wang Ping¹,Lu Hengyu¹,Argintaru Andreea¹,Chen Zhouliang¹,Glick Meir¹,Hao Huai-Xiang¹,Kato Mitsunori¹,Koenig Robert¹,LaRochelle Jonathan R.²^ORCID,Liu Gang¹,McNeill Eric¹,Majumdar Dyuti¹,Nishiguchi Gisele A.¹,Perez Lawrence B.¹,Paris Gregory¹,Quinn Christopher M.¹,Ramsey Timothy¹,Sendzik Martin¹,Shultz Michael David¹,Williams Sarah L.¹,Stams Travis¹,Blacklow Stephen C.²,Acker Michael G.¹,LaMarche Matthew J.¹^ORCID

Affiliation:

1. Novartis Institutes for Biomedical Research, Cambridge, Massachusetts 02139, United States

2. Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School and Department of Cancer Biology, Dana−Farber Cancer Institute, Boston, Massachusetts 02215, United States

Funder

National Cancer Institute

American Cancer Society

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00980

Reference44 articles.

1. Crystal Structure of the Tyrosine Phosphatase SHP-2

2. Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2