Extender Unit Promiscuity and Orthogonal Protein Interactions of an Aminomalonyl-ACP Utilizing Trans-Acyltransferase from Zwittermicin Biosynthesis
Author:
Affiliation:
1. Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695-8204, United States
2. Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina 27695-8204, United States
Funder
Division of Chemistry
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.8b00867
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1. Engineering enzymatic assembly lines for the production of new antimicrobials
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5. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis
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