Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain-Reference-Cited by-同舟云学术

Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain

Published:2018-11-07 Issue:12 Volume:13 Page:3374-3384
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Sharma Abhishek^ORCID,Toy Weiyi¹,Guillen Valeria Sanabria,Sharma Naina,Min Jian,Carlson Kathryn E.,Mayne Christopher G.,Lin Shengjia,Sabio Michael,Greene Geoffrey²,Katzenellenbogen Benita S.,Chandarlapaty Sarat¹,Katzenellenbogen John A.^ORCID

Affiliation:

1. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States

2. The Ben May Department for Cancer Research, University of Chicago, Chicago, Illinois 60637, United States

Funder

U.S. Department of Health and Human Services

Susan G. Komen for the Cure

U.S. Department of Defense

Breast Cancer Research Foundation

Virginia and D.K. Ludwig Fund for Cancer Research

University of Illinois

Stevens Institute of Technology

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.8b00877

Reference34 articles.

1. Estrogen Receptors: How Do They Signal and What Are Their Targets

2. Estrogen Receptors as Therapeutic Targets in Breast Cancer

3. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial

4. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

5. D538G Mutation in Estrogen Receptor-α: A Novel Mechanism for Acquired Endocrine Resistance in Breast Cancer

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