Enzymatic Formation of an Artificial Base Pair Using a Modified Purine Nucleoside Triphosphate

Author:

Flamme Marie123,Röthlisberger Pascal1,Levi-Acobas Fabienne1,Chawla Mohit4ORCID,Oliva Romina5,Cavallo Luigi4ORCID,Gasser Gilles3ORCID,Marlière Philippe6,Herdewijn Piet7ORCID,Hollenstein Marcel1ORCID

Affiliation:

1. Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France

2. Université Paris Descartes, Sorbonne Paris Cité, 12 rue de l’École de Médecine, 75006 Paris, France

3. Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005 Paris, France

4. King Abdullah University of Science and Technology (KAUST), Physical Sciences and Engineering Division, Kaust Catalysis Center, Thuwal, 23955-6900 Saudi Arabia

5. Department of Sciences and Technologies, University Parthenope of Naples, Centro Direzionale Isola C4, 80143, Naples, Italy

6. University of Paris Saclay, CNRS, iSSB, UEVE, Genopole, 5 Rue Henri Desbrueres, 91030 Evry, France

7. KU Leuven, Rega Institute for Medical Research, Medicinal Chemistry, Herestraat, 3000 Leuven, Belgium

Funder

Agence Nationale de la Recherche

Ministero dell?Istruzione, dell?Universit? e della Ricerca

King Abdullah University of Science and Technology

Institut Pasteur

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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