Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging

Author:

Iacovino Luca Giacinto1,Manzella Nicola2,Resta Jessica2,Vanoni Maria Antonietta3ORCID,Rotilio Laura1,Pisani Leonardo4ORCID,Edmondson Dale Edward5ORCID,Parini Angelo2,Mattevi Andrea1ORCID,Mialet-Perez Jeanne2,Binda Claudia1ORCID

Affiliation:

1. Department of Biology and Biotechnology, University of Pavia, Milan, Italy

2. Institute of Metabolic and Cardiovascular Diseases (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse, Toulouse, France

3. Department of Biosciences, University of Milan, Milan, Italy

4. Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Bari, Italy

5. Department of Biochemistry, Emory University, Atlanta, Georgia, United States

Funder

Agence Nationale de la Recherche

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Associazione Italiana per la Ricerca sul Cancro

Fondazione Cariplo

Fondation pour la Recherche M?dicale

F?d?ration Fran?aise de Cardiologie

R?gion Occitanie

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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