In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A-Reference-Cited by-同舟云学术

In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A

Published:2021-12-29 Issue:1 Volume:17 Page:118-128
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Xiao Xingqing¹^ORCID,Sarma Sudeep¹^ORCID,Menegatti Stefano¹²^ORCID,Crook Nathan¹^ORCID,Magness Scott T.³,Hall Carol K.¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States

2. Biomanufacturing Training and Education Center (BTEC), North Carolina State University, Raleigh, North Carolina 27695, United States

3. Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Division of Chemical, Bioengineering, Environmental, and Transport Systems

North Caroilna Biotechnology Center

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00743

Reference54 articles.

1. Risk factors for Clostridium difficile infection

2. Clostridium difficile Infection

3. Centers for Disease Control and Prevention. Nearly Half a Million Americans Suffered from Clostridium difficile infections in a Single Year. Available from: https://www.cdc.gov/media/releases/2015/p0225-clostridium-difficile.html (page last reviewed March 22, 2017 (archived document); cited Sept 20, 2018).

4. Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review

5. Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis

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