Antibacterial Synnepyrroles from Human-Associated <i>Nocardiopsis</i> sp. Show Protonophore Activity and Disrupt the Bacterial Cytoplasmic Membrane-Reference-Cited by-同舟云学术

Antibacterial Synnepyrroles from Human-Associated Nocardiopsis sp. Show Protonophore Activity and Disrupt the Bacterial Cytoplasmic Membrane

Published:2022-09-30 Issue:10 Volume:17 Page:2836-2848
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Zhang Lei¹^ORCID,Esquembre Lidia Alejo²,Xia Shu-Ning²^ORCID,Oesterhelt Filipp²,Hughes Chambers C.²³⁴^ORCID,Brötz-Oesterhelt Heike²³⁴^ORCID,Teufel Robin⁵^ORCID

Affiliation:

1. Faculty of Biology, University of Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany

2. Department of Microbial Bioactive Compounds, Interfaculty Institute for Microbiology and Infection Medicine, University of Tübingen, 72076 Tübingen, Germany

3. Cluster of Excellence EXC 2124: Controlling Microbes to Fight Infection, University of Tübingen, 72076 Tübingen, Germany

4. German Center for Infection Research, Partner Site Tübingen, 72076 Tübingen, Germany

5. Pharmaceutical Biology, Department of Pharmaceutical Sciences, Klingelbergstrasse 50, University of Basel, 4056 Basel, Switzerland

Funder

Deutsche Forschungsgemeinschaft

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00460