Combining Rational Design and Continuous Evolution on Minimalist Proteins That Target the E-box DNA Site
Author:
Affiliation:
1. Department of Chemistry, University of Toronto, 3359 Mississauga Road, Mississauga, ON L5L 1C6, Canada
Funder
Canadian Institutes of Health Research
University of Toronto
Social Sciences and Humanities Research Council of Canada
Natural Sciences and Engineering Research Council of Canada
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.0c00684
Reference80 articles.
1. TRANSCRIPTION FACTORS: Structural Families and Principles of DNA Recognition
2. Recognition of Specific DNA Sequences
3. E-Box Variants Direct Formation of Distinct Complexes with the Basic Helix-Loop-Helix Protein ALF1
4. Max-E47, a Designed Minimalist Protein That Targets the E-Box DNA Site in Vivo and in Vitro
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