Heparan Sulfate Mimicking Glycopolymer Prevents Pancreatic β Cell Destruction and Suppresses Inflammatory Cytokine Expression in Islets under the Challenge of Upregulated Heparanase-Reference-Cited by-同舟云学术

Heparan Sulfate Mimicking Glycopolymer Prevents Pancreatic β Cell Destruction and Suppresses Inflammatory Cytokine Expression in Islets under the Challenge of Upregulated Heparanase

Published:2022-06-04 Issue:6 Volume:17 Page:1387-1400
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Loka Ravi S.¹,Song Zhenfeng²,Sletten Eric T.³^ORCID,Kayal Yasmin⁴,Vlodavsky Israel⁴,Zhang Kezhong²,Nguyen Hien M.¹^ORCID

Affiliation:

1. Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States

2. Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48201, United States

3. Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United States

4. Cancer and Vascular Biology Research Center, Rappaport Faculty of Medicine, Technion − Israel Institute of Technology, Haifa 3525422, Israel

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00908

Reference59 articles.

1. Major Advances and Discoveries in Diabetes - 2019 in Review

2. Extracellular Matrix–Associated Factors Play Critical Roles in Regulating Pancreatic β-Cell Proliferation and Survival

3. Functions of Cell Surface Heparan Sulfate Proteoglycans

4. Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor

5. Molecular composition of the peri-islet basement membrane in NOD mice: a barrier against destructive insulitis

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