Development and Characterization of Mouse Monoclonal Antibodies Specific for Clostridiodes (Clostridium) difficile Lipoteichoic Acid-Reference-Cited by-同舟云学术

Development and Characterization of Mouse Monoclonal Antibodies Specific for Clostridiodes (Clostridium) difficile Lipoteichoic Acid

Published:2020-03-19 Issue:4 Volume:15 Page:1050-1058
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Cairns Chantelle M.¹,van Faassen Henk¹,St. Michael Frank¹,Aubry Annie¹,Henry Kevin A.¹,Rossotti Martin A.¹,Logan Susan M.¹,Hussack Greg¹,Gisch Nicolas²,Hogendorf Wouter F. J.³,Pedersen Christian M.³^ORCID,Cox Andrew D.¹^ORCID

Affiliation:

1. Vaccine and Emerging Infections Research, Human Health Therapeutics Research Centre, National Research Council, Ottawa, Ontario K1A 0R6, Canada

2. Division of Bioanalytical Chemistry, Priority Research Area Infections, Research Center Borstel, Leibniz Lung Center, 23845 Borstel, Germany

3. Department of Chemistry, University of Copenhagen, 2100 Copenhagen, Denmark

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.0c00066

Reference30 articles.

1. Clostridium difficileinfection: update on emerging antibiotic treatment options and antibiotic resistance

2. Treatment with Monoclonal Antibodies againstClostridium difficileToxins

3. Neutralization of Clostridium difficile Toxin A with Single-domain Antibodies Targeting the Cell Receptor Binding Domain

4. The host immune response to Clostridium difficile

5. A novel fusion protein containing the receptor binding domains of C. difficile toxin A and toxin B elicits protective immunity against lethal toxin and spore challenge in preclinical efficacy models

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