Stabilization of Glucocerebrosidase by Active Site Occupancy
Author:
Affiliation:
1. Department of Medical Biochemistry Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, The Netherlands
Funder
FP7 Ideas: European Research Council
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00276
Reference56 articles.
1. Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease.
2. A Deficiency of Glucocerebrosidase in Gaucher's Disease
3. Human acid beta-glucosidase. N-glycosylation site occupancy and the effect of glycosylation on enzymatic activity
4. LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase
5. Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2
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