A Gut-Restricted Lithocholic Acid Analog as an Inhibitor of Gut Bacterial Bile Salt Hydrolases-Reference-Cited by-同舟云学术

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A Gut-Restricted Lithocholic Acid Analog as an Inhibitor of Gut Bacterial Bile Salt Hydrolases

Published:2021-07-19 Issue:8 Volume:16 Page:1401-1412
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Adhikari Arijit A.¹,Ramachandran Deepti²,Chaudhari Snehal N.¹,Powell Chelsea E.¹,Li Wei¹,McCurry Megan D.¹,Banks Alexander S.²,Devlin A. Sloan¹^ORCID

Affiliation:

1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States

2. Division of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, United States

Funder

American Heart Association

Massachusetts Institute of Technology

National Institute of General Medical Sciences

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00192

Reference47 articles.

1. Small molecules from the human microbiota

2. Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

3. Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential

4. Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

5. Bile salt biotransformations by human intestinal bacteria

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