Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation-Reference-Cited by-同舟云学术

Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation

Published:2023-10-24 Issue:11 Volume:18 Page:2405-2417
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Thomas Adam M.¹,Serafini Marta¹^ORCID,Grant Emma K.²,Coombs Edward A. J.¹,Bluck Joseph P.¹³,Schiedel Matthias¹^ORCID,McDonough Michael A.¹,Reynolds Jessica K.¹,Lee Bernadette¹,Platt Michael¹,Sharlandjieva Vassilena⁴,Biggin Philip C.³^ORCID,Duarte Fernanda¹^ORCID,Milne Thomas A.⁴,Bush Jacob T.²^ORCID,Conway Stuart J.¹⁵^ORCID

Affiliation:

1. Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom

2. Department of Chemical Biology, GSK, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom

3. Department of Biochemistry, South Parks Road, Oxford OX1 3QU, United Kingdom

4. MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom

5. Department of Chemistry & Biochemistry, University of California Los Angeles, 607 Charles E. Young Drive East, P.O. Box 951569, Los Angeles, California 90095-1569, United States

Funder

Engineering and Physical Sciences Research Council

Medical Research Council

Agency for Science, Technology and Research

Fondazione AIRC per la ricerca sul cancro ETS

Deutsche Forschungsgemeinschaft

Biotechnology and Biological Sciences Research Council

St Hugh’s College, University of Oxford

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry