Exponential Combination of a and e/g Intracellular Peptide Libraries Identifies a Selective ATF3 Inhibitor
Author:
Affiliation:
1. Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom
2. Sapience Therapeutics, Inc. 500 Mamaroneck Ave. Suite 320, Tarrytown, New York 10591, United States
Funder
Sapience Therapeutics
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.3c00779
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1. Master Regulator Activating Transcription Factor 3 (ATF3) in Metabolic Homeostasis and Cancer
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3. The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells
4. WNT/β-Catenin Signaling Pathway Regulating T Cell-Inflammation in the Tumor Microenvironment
5. gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3
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