Discovery of a Small Molecule Probe of Rpn-6, an Essential Subunit of the 26S Proteasome
Author:
Affiliation:
1. Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 West Stadium Avenue, West Lafayette, Indiana 47907, United States
Funder
National Cancer Institute
School of Pharmacy, Purdue University
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b01019
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1. Overview of Proteasome Inhibitor-Based Anti-cancer Therapies: Perspective on Bortezomib and Second Generation Proteasome Inhibitors versus Future Generation Inhibitors of Ubiquitin-Proteasome System
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3. Regulation of proteasome activity in health and disease
4. The proteasome: Overview of structure and functions
5. An atomic structure of the human 26S proteasome
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