First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib-Reference-Cited by-同舟云学术

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib

Published:2016-10-12 Issue:11 Volume:11 Page:3179-3190
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

James Dominic I.¹,Smith Kate M.¹,Jordan Allan M.¹,Fairweather Emma E.¹,Griffiths Louise A.¹,Hamilton Nicola S.¹,Hitchin James R.¹,Hutton Colin P.¹,Jones Stuart¹,Kelly Paul¹,McGonagle Alison E.¹,Small Helen¹,Stowell Alexandra I. J.¹,Tucker Julie²,Waddell Ian D.¹,Waszkowycz Bohdan¹,Ogilvie Donald J.¹

Affiliation:

1. Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester, M20 4BX, United Kingdom

2. Structure and Biophysics, Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom

Funder

Cancer Research UK

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acschembio.6b00609

Reference52 articles.