A Complementary Chemical and Genomic Screening Approach for Druggable Targets in the Nrf2 Pathway and Small Molecule Inhibitors to Overcome Cancer Cell Drug Resistance-Reference-Cited by-同舟云学术

A Complementary Chemical and Genomic Screening Approach for Druggable Targets in the Nrf2 Pathway and Small Molecule Inhibitors to Overcome Cancer Cell Drug Resistance

Published:2018-03-22 Issue:5 Volume:13 Page:1189-1199
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Matthews James H.,Liang Xiao,Paul Valerie J.¹,Luesch Hendrik^ORCID

Affiliation:

1. Smithsonian Marine Station, 701 Seaway Drive, Fort Pierce, Florida 34949, United States

Funder

National Cancer Institute

Shenzhen Peacock Plan

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b01025

Reference48 articles.

1. The emerging role of the Nrf2–Keap1 signaling pathway in cancer

2. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

3. Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

4. Role of Nrf2 in Oxidative Stress and Toxicity

5. The KEAP1–NRF2 System in Cancer

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