Exploiting Overlapping Advantages of In Vitro and In Cellulo Selection Systems to Isolate a Novel High-Affinity cJun Antagonist
Author:
Affiliation:
1. Dept of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom
2. Isogenica Ltd., Chesterford Research Park, Little Chesterford, Essex CB10 1XL, United Kingdom
Funder
Biotechnology and Biological Sciences Research Council
Cancer Research UK
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00693
Reference51 articles.
1. AP-1: a double-edged sword in tumorigenesis
2. AP-1 as a regulator of cell life and death
3. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
4. Library construction, selection and modification strategies to generate therapeutic peptide-based modulators of protein–protein interactions
5. Transformation suppressor activity of a Jun transcription factor lacking its activation domain
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. An Approach to Derive Functional Peptide Inhibitors of Transcription Factor Activity;JACS Au;2022-04-06
2. The Role of AP-1 Transcription Factors in Plasma Cell Biology and Multiple Myeloma Pathophysiology;Cancers;2021-05-12
3. Peptide library screening as a tool to derive potent therapeutics: current approaches and future strategies;Future Medicinal Chemistry;2021-01
4. Selective antagonism of cJun for cancer therapy;Journal of Experimental & Clinical Cancer Research;2020-09-11
5. Coupling Computational and Intracellular Screening and Selection Toward Co-compatible cJun and cFos Antagonists;Biochemistry;2019-12-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3