Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses-Reference-Cited by-同舟云学术

Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses

Published:2019-04-02 Issue:5 Volume:14 Page:857-872
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Slivka Peter F.¹^ORCID,Hsieh Chen-Lin²,Lipovsky Alex¹,Pratt Steven D.³,Locklear John³⁴,Namovic Marian T.³,McDonald Heath A.⁵,Wetter Joseph⁵,Edelmayer Rebecca⁵,Hu Min²,Murphy Erin²,Domanus Marc²,Lu Charles²,Duggan Ryan⁶,King Jacob¹,Scott Victoria E.⁵,Donnelly-Roberts Diana³,Slavin Anthony⁷,Gopalakrishnan Sujatha³,Chung Namjin²,Goedken Eric R.¹

Affiliation:

1. Discovery Dermatology & Fibrosis, AbbVie Bioresearch Center, Worcester, Massachusetts 01605, United States

2. Genomics Research Center, AbbVie Inc., North Chicago, Illinois 60064, United States

3. Target Enabling Science & Technology, AbbVie Inc., North Chicago, Illinois 60064, United States

4. PerkinElmer Life Sciences, Waltham, Massachusetts 02451, United States

5. Discovery Dermatology & Fibrosis, AbbVie Inc., North Chicago, Illinois 60064, United States

6. Immuno-Oncology Discovery, AbbVie Inc., North Chicago, Illinois 60064, United States

7. Immunology Pharmacology, AbbVie Bioresearch Center, Worcester, Massachusetts 01605, United States

Funder

AbbVie

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.8b00260

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