Targeting Regorafenib-Induced Toxicity through Inhibition of Gut Microbial β-Glucuronidases-Reference-Cited by-同舟云学术

Targeting Regorafenib-Induced Toxicity through Inhibition of Gut Microbial β-Glucuronidases

Published:2019-10-30 Issue:12 Volume:14 Page:2737-2744
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Ervin Samantha M.¹,Hanley Ronan P.²,Lim Lauren¹,Walton William G.¹,Pearce Kenneth H.²,Bhatt Aadra P.³,James Lindsey I.²^ORCID,Redinbo Matthew R.¹⁴^ORCID

Affiliation:

1. Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

2. Center for Integrative Chemical Biology and Drug Discovery, Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

4. Integrated Program for Biological and Genome Sciences and Departments of Biochemistry and Microbiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Funder

U.S. Department of Health and Human Services

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00663

Reference42 articles.

1. Regorafenib: A Review in Metastatic Colorectal Cancer

2. Regorafenib as a single-agent in the treatment of patients with gastrointestinal tumors: an overview for pharmacists