Identification of Bioactive Small Molecule Inhibitors of Separase-Reference-Cited by-同舟云学术

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Identification of Bioactive Small Molecule Inhibitors of Separase

Published:2019-09-30 Issue: Volume: Page:
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Henschke Lars¹,Frese Matthias²,Hellmuth Susanne³,Marx Andreas²^ORCID,Stemmann Olaf³,Mayer Thomas U.¹^ORCID

Affiliation:

1. Department of Biology and Konstanz Research School Chemical-Biology (KoRS-CB), University of Konstanz, Universitätsstraße 10, 78467 Konstanz, Germany

2. Department of Chemistry and Konstanz Research School Chemical-Biology (KoRS-CB), University of Konstanz, Universitätsstraße 10, 78467 Konstanz, Germany

3. Chair of Genetics, University of Bayreuth, Universitätsstraße 30, 95440 Bayreuth, Germany

Funder

Deutsche Forschungsgemeinschaft

Konstanz Research School Chemical Biology

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00661

Reference23 articles.

1. Causes and consequences of aneuploidy in cancer

2. Mitosis: a history of division

3. The sister bonding of duplicated chromosomes

4. Cohesion and cohesin-dependent chromatin organization

5. Cohesin Cleavage by Separase Required for Anaphase and Cytokinesis in Human Cells

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Walrycin B, as a novel separase inhibitor, exerts potent anticancer efficacy in a mouse xenograft model;Biochemical Pharmacology;2024-11

2. Live Cell Monitoring of Separase Activity, a Key Enzymatic Reaction for Chromosome Segregation, with Chimeric FRET-Based Molecular Sensor upon Cell Cycle Progression;Biosensors;2024-04-15

3. Recent advances in the colorimetric and fluorescence analysis of bioactive small-molecule compounds based on the enzyme-like activity of nanomaterials;Journal of Pharmaceutical and Biomedical Analysis;2023-11

4. Separase and Roads to Disengage Sister Chromatids during Anaphase;International Journal of Molecular Sciences;2023-02-27

5. Protease-triggered bioresponsive drug delivery for the targeted theranostics of malignancy;Acta Pharmaceutica Sinica B;2021-08

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