Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct-Reference-Cited by-同舟云学术

Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct

Published:2024-02-06 Issue:2 Volume:19 Page:392-406
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Zehe Markus¹^ORCID,Kehrein Josef¹^ORCID,Schollmayer Curd¹,Plank Christina¹²,Kovacs Helena³,Merino Asumendi Eduardo¹^ORCID,Holzgrabe Ulrike¹^ORCID,Grimm Clemens²,Sotriffer Christoph¹^ORCID

Affiliation:

1. University of Würzburg, Institute of Pharmacy and Food Chemistry, Am Hubland, DE-97074 Würzburg, Germany

2. University of Würzburg, Department of Biochemistry and Cancer Therapy Research Center (CTRC), Theodor-Boveri-Institute, Am Hubland, DE-97074 Würzburg, Germany

3. Bruker Switzerland AG, Industriestrasse 26, CH-8117 Fällanden, Switzerland

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.3c00589

Reference67 articles.

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5. HSP70 and HSP90 in Cancer: Cytosolic, Endoplasmic Reticulum and Mitochondrial Chaperones of Tumorigenesis

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