The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR-Reference-Cited by-同舟云学术

The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR

Published:2017-03-27 Issue:5 Volume:12 Page:1297-1307
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Bieri Raphael¹²,Scherr Nicole¹²,Ruf Marie-Thérèse¹²,Dangy Jean-Pierre¹²^ORCID,Gersbach Philipp³,Gehringer Matthias³,Altmann Karl-Heinz³,Pluschke Gerd¹²^ORCID

Affiliation:

1. Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland

2. University of Basel, Petersplatz 1, 4003 Basel, Switzerland

3. Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zürich, Vladimir-Prelog-Weg 1-5/10, 8093 Zürich, Switzerland

Funder

Stop Buruli Consortium funded by the UBS Optimus Foundation

Medicor Foudation

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00053

Reference49 articles.

1. Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

2. Histopathologic Features ofMycobacterium ulceransInfection