Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer

Author:

Kohnz Rebecca A.1,Mulvihill Melinda M.1,Chang Jae Won2,Hsu Ku-Lung3,Sorrentino Antonio,Cravatt Benjamin F.2,Bandyopadhyay Sourav,Goga Andrei4,Nomura Daniel K.1

Affiliation:

1. Program in Metabolic Biology, Department of Nutritional Sciences and Toxicology, University of California, Berkeley, 127 Morgan Hall, Berkeley, California 94720, United States

2. Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Rd. SR107, La Jolla, California 92037, United States

3. Department of Chemistry, University of Virginia, McCormick Road, P.O. Box 400319, Charlottesville, Virginia 22904-4319, United States

4. University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, Box 0128, San Francisco, California 94143, United States

Funder

National Cancer Institute

Chicago Community Trust

Congressionally Directed Medical Research Programs

American Cancer Society

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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