Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins-Reference-Cited by-同舟云学术

Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins

Published:2016-01-14 Issue:4 Volume:11 Page:864-868
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

King Andrew M.¹,King Dustin T.²,French Shawn¹,Brouillette Eric³,Asli Abdelhamid³,Alexander J. Andrew N.²,Vuckovic Marija²,Maiti Samarendra N.⁴,Parr Thomas R.⁵,Brown Eric D.¹,Malouin François³,Strynadka Natalie C. J.²,Wright Gerard D.¹

Affiliation:

1. M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario L8S 4K1, Canada

2. The Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia. 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada

3. Centre d’Etude et de Valorisation de la Diversité Microbienne (CEVDM), Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada J1K 2R1

4. NAEJA Pharmaceutical, Inc., Edmonton, Alberta T6E 5V2, Canada

5. Fedora Pharmaceutical, Inc., Edmonton, Alberta T6E 5V2, Canada

Funder

Howard Hughes Medical Institute

Canadian Institutes of Health Research

Canada Foundation for Innovation

Canada Research Chairs

Natural Sciences and Engineering Research Council of Canada

British Columbia Knowledge Development Fund

Publisher

American Chemical Society (ACS)

Subject