Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor

Author:

Krainz Tanja1,Lamade Andrew M.2,Du Lina2,Maskrey Taber S.1,Calderon Michael J.3,Watkins Simon C.3,Epperly Michael W.4,Greenberger Joel S.4,Bayır Hülya256,Wipf Peter1,Clark Robert S. B.26ORCID

Affiliation:

1. Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

2. Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, United States

3. Department of Cell Biology, Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

4. Department of Radiation Oncology, Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15232, United States

5. Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15224, United States

6. Children’s Neuroscience Institute, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224, United States

Funder

National Institutes of Health

UNKNOWN

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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