GLI1 Inhibitors Identified by Target Protein Oriented Natural Products Isolation (TPO-NAPI) with Hedgehog Inhibition-Reference-Cited by-同舟云学术

GLI1 Inhibitors Identified by Target Protein Oriented Natural Products Isolation (TPO-NAPI) with Hedgehog Inhibition

Published:2018-08-30 Issue:9 Volume:13 Page:2551-2559
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Arai Midori A.¹^ORCID,Ochi Fumie¹,Makita Yoshinori¹,Chiba Tetsuhiro²,Higashi Kyohei³,Suganami Akiko²,Tamura Yutaka²,Toida Toshihiko¹,Iwama Atsushi²⁴,Sadhu Samir K.⁵,Ahmed Firoj⁶,Ishibashi Masami¹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan

2. Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan

3. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan

4. The Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan

5. Pharmacy Discipline, Khulna University, Khulna-9208, Bangladesh

6. Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000, Bangladesh

Funder

Naito Foundation

Chiba University

Takeda Science Foundation

Astellas Foundation for Research on Metabolic Disorders

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.8b00492

Reference48 articles.

1. Roles for Hedgehog signaling in adult organ homeostasis and repair

2. Hedgehog signalling in cancer formation and maintenance

3. Hedgehog signalling pathway inhibitors as cancer suppressing agents

4. Sonic Hedgehog in cancer stem cells: a novel link with autophagy

5. Control of stem cells and cancer stem cells by Hedgehog signaling: Pharmacologic clues from pathway dissection

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