Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme

Author:

Cho Su-Hee1,Kim Seung-Young2,Tomita Takeo1,Shiraishi Taro1,Park Jin-Soo1,Sato Shusuke3,Kudo Fumitaka3,Eguchi Tadashi3ORCID,Funa Nobutaka2,Nishiyama Makoto1ORCID,Kuzuyama Tomohisa1ORCID

Affiliation:

1. Biotechnology Research Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan

2. Department of Food Science and Biotechnology, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

3. Department of Chemistry, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8551, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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