In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish

Author:

Sasagawa Shota1,Nishimura Yuhei12345,Koiwa Junko1,Nomoto Tsuyoshi6,Shintou Taichi6,Murakami Soichiro1,Yuge Mizuki1,Kawaguchi Koki1,Kawase Reiko1,Miyazaki Takeshi6,Tanaka Toshio12345

Affiliation:

1. Department of Molecular and Cellular Pharmacology, Pharmacogenomics and Pharamacoinformatics, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan

2. Mie University Medical Zebrafish Research Center, Tsu, Mie 514-8507, Japan

3. Depertment of Systems Pharmacology, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan

4. Department of Omics Medicine, Mie University Industrial Technology Innovation Institute, Tsu, Mie 514-8507, Japan

5. Department of Bioinformatics, Mie University Life Science Research Center, Tsu, Mie 514-8507, Japan

6. Corporate R&D Headquarters, Canon Inc., Ohta-ku, Tokyo 146-8501, Japan

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Japan Chemical Industry Association

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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