Probing the Role of Murine Neuroglobin CDloop–D-Helix Unit in CO Ligand Binding and Structural Dynamics

Author:

Exertier Cécile1,Sebastiani Federico2,Freda Ida1,Gugole Elena1,Cerutti Gabriele3,Parisi Giacomo4,Montemiglio Linda Celeste5,Becucci Maurizio2,Viappiani Cristiano6ORCID,Bruno Stefano7,Savino Carmelinda5,Zamparelli Carlotta1,Anselmi Massimiliano8,Abbruzzetti Stefania6,Smulevich Giulietta2ORCID,Vallone Beatrice1ORCID

Affiliation:

1. Dipartimento di Scienze Biochimiche “A. Rossi Fanelli”, Sapienza, Università di Roma, Piazzale A. Moro 5, I-00185 Rome, Italy

2. Dipartimento di Chimica ″Ugo Schiff″, Università di Firenze, Via della Lastruccia 3-13, I-50019 Sesto Fiorentino, Italy

3. Zuckerman Mind Brain Behavior Institute, Columbia University, 3227 Broadway, New York, New York 10027, United States

4. Center for Life Nanoscience, Istituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161 Rome, Italy

5. Institute of Molecular Biology and Pathology, National Research Council, Piazzale A. Moro 5, 00185 Rome, Italy

6. Department of Mathematical, Physical and Computer Sciences, University of Parma, Parco Area delle Scienze, 7/A, I-43124 Parma, Italy

7. Department of Food and Drugs, University of Parma, Parco Area delle Scienze 27/A, I-43124 Parma, Italy

8. Theoretical Physics and Center for Biophysics, Saarland University, Campus E2 6, 66123 Saarbrücken, Germany

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Sapienza Universit? di Roma

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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