Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers-Reference-Cited by-同舟云学术

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Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers

Published:2024-06-03 Issue:6 Volume:19 Page:1339-1350
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Theodoropoulos Panayotis C.¹²,Guo Holly H.¹²,Wang Wentian¹,Crossley Eric¹,Rivera Cancel Giomar¹²,Fang Min¹,Nguyen Thu¹²,Baniasadi Hamid¹,Williams Noelle S.¹,Ready Joseph M.¹^ORCID,De Brabander Jef K.¹^ORCID,Nijhawan Deepak¹²^ORCID

Affiliation:

1. Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

2. Department of Internal Medicine, Program in Molecular Medicine and Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

Funder

Welch Foundation

University of Texas Southwestern Medical Center

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.4c00170

Reference28 articles.

1. Management and prognosis of malignant peripheral nerve sheath tumors: The experience of the French Sarcoma Group (GSF-GETO)

2. Preclinical Therapeutic Efficacy of a Novel Pharmacologic Inducer of Apoptosis in Malignant Peripheral Nerve Sheath Tumors

3. Plasma concentrations of water-soluble vitamins in metabolic syndrome subjects

4. Niacin for dairy cattle: a review

5. The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

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