Rational Design of a Dephosphorylation-Resistant Reporter Enables Single-Cell Measurement of Tyrosine Kinase Activity
Author:
Affiliation:
1. Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 and North Carolina State University, Raleigh, North Carolina 27695, United States
Funder
National Cancer Institute
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.5b00667
Reference45 articles.
1. Oncogenic kinase signalling
2. Cell Signaling by Receptor Tyrosine Kinases
3. Tyrosine Kinases as Targets for Cancer Therapy
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5. The challenges posed by cancer heterogeneity
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