Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products

Author:

Ahmed Muhammad N.12,Wahlsten Matti1ORCID,Jokela Jouni1ORCID,Nees Matthias34,Stenman Ulf-Håkan2,Alvarenga Danillo O.15ORCID,Strandin Tomas6,Sivonen Kaarina1ORCID,Poso Antti78ORCID,Permi Perttu910,Metsä-Ketelä Mikko11ORCID,Koistinen Hannu2,Fewer David P.1ORCID

Affiliation:

1. Department of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Viikinkaari 9, Biocenter 1, P.O. Box 56, Helsinki FIN-00014, Finland

2. Department of Clinical Chemistry and Haematology, Faculty of Medicine, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 8, P.O. Box 63, Helsinki FIN-00014, Finland

3. Department of Biochemistry and Molecular Biology, Medical University in Lublin, ul. Chodzki 1, Lublin 20-093, Poland

4. Institute of Biomedicine and Western Cancer Centre FICAN West, University of Turku, Turku 20101, Finland

5. Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen DK-2100, Denmark

6. Department of Virology, Faculty of Medicine, University of Helsinki, Haartmaninkatu 3, P.O. Box 21, Helsinki FIN-00014, Finland

7. School of Pharmacy, University of Eastern Finland, P.O. Box 1627, Kuopio FIN-70211, Finland

8. Dept. of Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Strasse 14, Tübingen DE-72076, Germany

9. Department of Biological and Environmental Science, University of Jyväskylä, P.O. Box 35, Jyväskylä FI-40014, Finland

10. Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box 35, Jyväskylä FI-40014, Finland

11. Department of Biochemistry, University of Turku, Turku FIN-20014, Finland

Funder

Sigrid Jus??liuksen S????ti??

Funda????o de Amparo ?? Pesquisa do Estado de S??o Paulo

Academy of Finland

Jane ja Aatos Erkon S????ti??

Helsingin Yliopisto

NordAqua

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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