Structure–Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch

Author:

Vicens Quentin1ORCID,Mondragón Estefanía1,Reyes Francis E.1,Coish Philip2,Aristoff Paul3,Berman Judd4,Kaur Harpreet4,Kells Kevin W.4,Wickens Phil4,Wilson Jeffery4,Gadwood Robert C.5,Schostarez Heinrich J.5,Suto Robert K.6,Blount Kenneth F.2,Batey Robert T.1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of Colorado, 596 UCB, Boulder, Colorado 80309, United States

2. BioRelix Inc., 124 Washington Street, Foxborough, Massachusetts 02035, United States

3. Aristoff Consulting LLC, 3726 Green Spring Drive, Fort Collins, Colorado 80528, United States

4. Dalton Pharma Services, 349 Wildcat Road, Toronto, ON M3J 2S3, Canada

5. Kalexsyn, Inc., 4502 Campus Drive, Kalamazoo, Michigan 49008, United States

6. Xtal BioStructures, Inc., 12 Michigan Drive, Natick, Massachusetts 01760, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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1. Transcriptome-Wide, Unbiased Profiling of Ribonuclease Targeting Chimeras;Journal of the American Chemical Society;2024-07-24

2. Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN;Nature Communications;2024-07-08

3. Prospects for Riboswitches in Drug Development;Methods and Principles in Medicinal Chemistry;2024-07-05

4. Advances in machine-learning approaches to RNA-targeted drug design;Artificial Intelligence Chemistry;2024-06

5. Flipping the script: Understanding riboswitches from an alternative perspective;Journal of Biological Chemistry;2024-03

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