Targeting Ribonucleases with Small Molecules and Bifunctional Molecules
Author:
Affiliation:
1. Chemical Genomics Centre, Max Planck Institute of Molecular Physiology, Otto-Hahn-Str. 11, Dortmund 44227, Germany
2. Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Str. 11, Dortmund 44227, Germany
Funder
AstraZeneca
Bundesministerium für Bildung und Forschung
Merck KGaA
Pfizer
Max-Planck-Gesellschaft
Boehringer Ingelheim Stiftung
Volkswagen Foundation
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.3c00191
Reference143 articles.
1. Ribonucleases as Drug Targets
2. Structure-function relationships in human ribonucleases: main distinctive features of the major RNase types
3. A scientific journey through the 2-5A/RNase L system
4. Information available at cut rates: structure and mechanism of ribonucleases
5. New advances in our understanding of the “unique” RNase L in host pathogen interaction and immune signaling
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