Reversible Assembly of Proteolysis Targeting Chimeras-Reference-Cited by-同舟云学术

Reversible Assembly of Proteolysis Targeting Chimeras

Published:2023-07-09 Issue:7 Volume:18 Page:1582-1593
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Gui Weijun¹,Giardina Sarah F.²^ORCID,Balzarini Madeline¹,Barany Francis²,Kodadek Thomas¹^ORCID

Affiliation:

1. Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 120 Scripps Way, Jupiter, Florida 33458, United States

2. Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.3c00199

Reference54 articles.

1. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

2. Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

3. Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

4. Phthalimide conjugation as a strategy for in vivo target protein degradation

5. Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

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