2,7-Diaminomitosene, a Monofunctional Mitomycin C Derivative, Alkylates DNA in the Major Groove. Structure and Base-Sequence Specificity of the DNA Adduct and Mechanism of the Alkylation-Reference-Cited by-同舟云学术

2,7-Diaminomitosene, a Monofunctional Mitomycin C Derivative, Alkylates DNA in the Major Groove. Structure and Base-Sequence Specificity of the DNA Adduct and Mechanism of the Alkylation

Published:1996-01-01 Issue:39 Volume:118 Page:9209-9217
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Suresh Kumar Gopinatha¹,Musser Steven M.¹,Cummings Jeffrey¹,Tomasz Maria¹

Affiliation:

1. Contribution from the Department of Chemistry, Hunter College, City University of New York, New York 10021, Instrumentation and Biophysics Branch, U.S. Food and Drug Administration, 200 C Street, S.W., Washington, D.C. 20204, and Imperial Cancer Research Fund, Western General Hospital, Edinburgh, Scotland

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja9607401

Reference56 articles.

1. Szybalski, W.; Iyer, V. N. InAntibiotics 1: Mechanism of action; Gottlieb, D., Shaw, P. D., Eds.; Springer-Verlag: New York, 1967; pp 230−245.

2. Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct.

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