The Discodermolide Hairpin Structure Flows from Conformationally Stable Modular Motifs
Author:
Affiliation:
1. Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322
2. Faculty of Chemical Sciences and Technologies, University of Rome “Tor Vergata”, 00173 Rome, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9015284
Reference69 articles.
1. Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta
2. Microtubule Interactions with Chemically Diverse Stabilizing Agents: Thermodynamics of Binding to the Paclitaxel Site Predicts Cytotoxicity
3. Designer Discodermolide Segments via Ozonolysis of Vinyl Phosphonates
4. Total Synthesis of Discodermolide: Optimization of the Effective Synthetic Route
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